A nanodiamond for structural biomimetic scaffolds
Keywords:
hybrid nano-composites, biomaterials, bioactive scaffolds, bioengineering, biomedicalAbstract
Bio-mechanically active scaffolds for tissue engineering combining hydrophilic polymeric matrix and nano-diamond fillers properties are presented and discussed in this paper. The resulting scaffolding materials revealed remarkable mechanical and biological properties to be exploited in advanced biomedical applications. The novel hybrid material is based on 2 and 5 volume % of detonation nano-diamond particles in a hydrophilic poly-(hydroxyl-ethylmethacrylate) matrix. According to its mechanical and biological properties, the nanocomposite shows a hybrid nature. The base analytical procedures for the preparation of the hybrid nanocomposites and some preliminary mechanical characteristics are presented. The proposed hybrid system has been considered for potential biomimetic, osteoconductive and osteoinductive scaffolds application in bio-mechanically active bone scaffolds for osteoblast and stem cell differentiation and growth. These more rigid hybrid nano-composites are predicted to possess improved mechanical strength overcoming the mechanical weaknesses of traditional hydrogels clinically utilized for bone regeneration.Downloads
Published
Issue
Section
License
Engineering review uses the Creative Commons Attribution-NonCommercial-NoDerivatives (CC-BY-NC-ND) 4.0 International License, which governs the use, publishing and distribution of articles by authors, publishers and the wider general public.
The authors are allowed to post a digital file of the published article, or the link to the published article (Enginering Review web page) may be made publicly available on websites or repositories, such as the Author’s personal website, preprint servers, university networks or primary employer’s institutional websites, third party institutional or subject-based repositories, and conference websites that feature presentations by the Author(s) based on the published article, under the condition that the article is posted in its unaltered Engineering Review form, exclusively for non-commercial purposes.
The journal Engineering Review’s publishing procedure is performed in accordance with the publishing ethics statements, defined within the Publishing Ethics Resource Kit. The Ethics statement is available in the document Ethics Policies.